The Zerg and Zen potions have been added thanks to Calamity, which respectively raise and lower enemy spawn rates by massive amounts.1.5 later even added a new generation system which causes them to spawn in larger veins, as well as at fixed depths depending on their rarity.
Calamity adds a series of underground "Crawler" enemies which spawn uncommonly and drop their namesake gemstones, making it much easier to keep a supply. While you don't need them for a lot, it's still pretty troublesome having to dive down when you run short.
Wearing Bloodflare armor expedites this by heavily increasing the chance for Blood Moons and enemies to drop blood orbs, which greatly increases the overall yield over a period of time.
Made even more apparent with the update that made specialized variants of the Auric Tesla Armor - his armor still resembles the old Master of All armor that combined almost all the perks of the current variants into one set. This also gets inverted somewhat - one of his family's superweapons, the Astreal Defeat, is eventually used as a material for the far stronger Heavenly Gale (and that can be further upgraded into the Drataliornus). His official appearance shows him clad in what appears to be a mechanically augmented version of the armor, fueled by his Stims.